Hypertension in the elderly with frailty
Conditions
Interventions
Experimental Group:Treatment with modified Qishen Liwei formula combined with conventional therapy. Composition of the herbal formula: Qishen Liwei formula (Radix Astragali 30g, Radix Salviae Miltiorr
Control Group:Conventional treatment
Sponsors
Beijing University of Chinese Medicine Oriental Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for elderly hypertension and has had home-measured or inpatient blood pressure within the range of 90 mmHg =Systolic Blood Pressure= 150 mmHg and/or 60 mmHg =Diastolic Blood Pressure= 90 mmHg for three consecutive days prior to enrollment; (2) Meets the diagnostic criteria for frailty; (3) Patients diagnosed with qi deficiency and blood stasis, and/or spleen-kidney deficiency according to traditional Chinese medicine (TCM) differentiation; (4) No use of TCM herbal decoctions or finished TCM products in the past two weeks; (5) Voluntarily participates and signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with secondary hypertension; (2) Patients with concurrent diseases in the acute phase (e.g., acute coronary syndrome, acute cerebrovascular disease, active bleeding in hemorrhagic diseases, acute gout attack, infectious diseases, fractures, etc.); (3) Patients with unstable vital signs, bedridden status, or NYHA class IV heart failure; (4) Patients with any of the following conditions: severe arrhythmias (e.g., atrial fibrillation with rapid ventricular response, atrial flutter, paroxysmal ventricular tachycardia, etc.), pulmonary heart disease, rheumatic heart disease, myocarditis, cardiomyopathy, aortic dissection, pulmonary embolism, or other severe conditions; (5) Patients with serum alanine aminotransferase or serum creatinine levels exceeding twice the upper limit of the normal reference range.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fried Frailty Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Score;blood pressure control level; | — |
Countries
China
Contacts
Public ContactZhou Kun
Beijing University of Chinese Medicine Oriental Hospital
Outcome results
None listed