acute ischemic stroke
Conditions
Interventions
Experimental Group:Phlegm-Resolving and Stasis-Dispelling Formula + Guideline-Based Standardized Internal Medical Drug Therapy
Control Group:Evidence-based standardized internal medicine drug therapy.
Sponsors
Zhejiang Provincial Li Tongde Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 )Meets the diagnostic criteria for acute ischemic stroke and corresponds to the traditional Chinese medicine syndrome type "wind-phlegm obstructing the meridians"; 2) Onset within 24 hours; 3) Age between 18 and 80 years (inclusive); 4) NIHSS score between 3 and 25 (inclusive); 5) Patient or legal representative has been informed and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who have accepted or areto undergo intravenous thrombolysis or endovascular interventional therapy (including mechanical thrombectomy, arterial thrombolysis, and angioplasty); 2. Patients with stroke caused by brain tumors, brain trauma, or hematological diseases, as confirmed by examination; 3. Patients with a history of stroke and residual sequelae affecting outcome assessment, i.e., those with a pre-stroke mRS score =2; 4. Patients with atrial fibrillation, rheumatic heart disease, valvular heart disease, or other conditions that may lead to cardioembolic events; 5. Patients with conditions such as claudication, osteoarthritis, rheumatoid arthritis, or gouty arthritis that impair limb mobility and affect neurological examination; 6. Patients with severe liver or kidney dysfunction (Note: Liver dysfunction refers to ALT or AST levels greater than 2 times the upper limit of normal; kidney dysfunction refers to serum creatinine levels greater than 2 times the upper limit of normal); 7. Patients with other life-threatening severe diseases with an expected survival time of less than 3 months; 8. Patients with other diseases that may limit neurological function evaluation or affect follow-up; 9. Pregnant women, those planning pregnancy, or breastfeeding women; 10. Patients currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| National Institutes of Health Stroke Scale (NIHSS);Glasgow Coma Scale;Barthel Index; | — |
Countries
China
Contacts
Public ContactZhang Zhenzhong
Zhejiang Provincial Li Tongde Hospital
Outcome results
None listed