Knee osteoarthritis
Conditions
Interventions
Control Group:Conventional Massage
Observation group:Chen Yuan's Ointment Rubbing Method
Sponsors
Hospital of Traditional Chinese Medicine of Xinjiang Uygur Autonomous Region
Eligibility
Sex/Gender
All
Age
38 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Meet above diagnostic criteria; 2) Imaging grade =III; 3) Age 38-70, any gender; 4) No knee surgery history, no recent treatment within past month; 5) For bilateral cases meeting criteria, assess more symptomatic side; 6) Voluntary participation with signed informed consent, strict adherence to protocol;
Exclusion criteria
Exclusion criteria: 1)Secondary knee osteoarthritis from other systemic diseases; 2) Acute knee injuries, significant effusion, ligament tears, meniscus rupture; 3)Comorbid fractures, tumors, tuberculosis, rheumatoid diseases affecting knee structure/function; 4) Contraindications for massage: local skin infection, hematologic disorders, severe organic diseases, pregnancy, mental confusion; 5) Participation in other trials or self-medication;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Color Doppler Ultrasound for Suprapatellar Bursa Effusion and Synovial Blood Flow;Gait Analysis;Fecal - gut microbiota changes (16S microbial diversity sequencing, LC-MS targeted metabolomics, metagenomic sequencing); | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) Osteoarthritis Assessment Scale; | — |
Countries
China
Contacts
Public ContactLiu Junchang
Xinjiang Medical University
Outcome results
None listed