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Efficacy and Neural Mechanisms of Acupoint Pressure for Alleviating Acupuncture-Induced Pain: A Functional Imaging Analysis Based on Zusanli (ST36) Acupoint

Efficacy and Neural Mechanisms of Acupoint Pressure for Alleviating Acupuncture-Induced Pain: A Functional Imaging Analysis Based on Zusanli (ST36) Acupoint

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000163
Enrollment
Unknown
Registered
2026-01-24
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acupuncture-Induced Pain

Interventions

AB Group:Intervention A is administered in period 1, followed by intervention B in period 2 after a 1-week washout period.
BA Group:Intervention B is administered in period 1, followed by intervention A in period 2 after a 1-week washout period.

Sponsors

Wuhan Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Aged 18–60 years; 2) In good general health; 3) No skin lesions or damage at the acupuncture sites; 4) No use of analgesic medications within the past 3 months; 5) Good compliance, willingness to participate in the study, and provision of written informed consent. Note: Only volunteers who meet all five of the above criteria will be eligible for inclusion in this study.

Exclusion criteria

Exclusion criteria: 1) Individuals with an aversion to or intolerance of acupuncture; 2) Pregnant or breastfeeding women; 3) Individuals with a history of alcohol abuse or substance abuse. Note: Volunteers who meet any one of the above criteria will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
functional near-infrared spectroscopy;visual analog scale;

Secondary

MeasureTime frame
massachusetts general hospital acupuncture sensation scales;state anxiety inventory;incidence of adverse events;incidence of serious adverse events;

Countries

China

Contacts

Public ContactWenyan Wang

Wuhan Hospital of Traditional Chinese Medicine

wwy841001@163.com15377082220

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 7, 2026