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Decoding the Power of Cinnamon Leaf Oil Alleviates Seasonal Mood Disorders and Improves Parkinson's Disease Outcomes: A Randomized Trial

Decoding the Power of Cinnamon Leaf Oil Alleviates Seasonal Mood Disorders and Improves Parkinson's Disease Outcomes: A Randomized Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000162
Enrollment
Unknown
Registered
2026-01-24
Start date
2024-11-30
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinsons Disease

Interventions

Control Group:Placebo intervention: Inhalation of atomized distilled water in the same volume, with the same time and frequency as the intervention group. All patients received standard PD drug therap
Intervention Group:Cinnamon essential oil inhalation therapy: 2 times daily (09:00-10:00, 15:00-16:00), 60 minutes each time, concentration 50±5 ppm, using a medical ultrasonic nebulizer (particle siz

Sponsors

Jining Polytechnic, Medical and Health Industry College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients with Parkinson's disease who meet the diagnostic criteria for Parkinson's disease of the Movement Disorders Society (MDS-UPDRS); 2.Aged between 40 and 80 years old with a disease course of 1 to 10 years; 3.The scores of Hamilton Depression Scale/Hamilton Anxiety Scale (HAMD/HAMA) in winter are = 14 points; 4.Willingly sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Severe cardiovascular and cerebrovascular diseases malignant tumors or schizophrenia; 2.Allergy to cinnamaldehyde or aromatic agents; 3.Participation in other clinical trials within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Hamilton Anxiety Rating Scale (HAMA);Hamilton Depression Rating Scale (HAMD);Activities of Daily Living Scale ;

Secondary

MeasureTime frame
Pittsburgh Sleep Quality Index (PSQI);Fatigue Scale-14 (FS-14);Adverse event records;

Countries

China

Contacts

Public Contactzhangqiang

Jining Polytechnic

bow202112@163.com+8615887024890

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 7, 2026