Type 2 diabetes and stable angina pectoris comorbidities
Conditions
Interventions
Qihu Geqi Granules Group:Take Qihu Geqi Granules orally + Basic treatment + Lifestyle intervention
Sponsors
Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria for Type 2 Diabetes or have been diagnosed with Type 2 Diabetes; (2) Meeting the diagnostic criteria for coronary heart disease and stable angina pectoris, with angina pectoris severity classified as grade I or Grade II, and having more than two episodes per week; (3) It meets the diagnostic criteria for the syndrome of qi and Yin deficiency with blood stasis in traditional Chinese medicine; (4) Be between 18 and 75 years old (inclusive). (5) Those who agree to sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Chest pain caused by acute coronary syndrome, aortic dissection or other reasons; (2) Those who have newly developed acute myocardial infarction, stroke or undergone coronary percutaneous coronary intervention within 3 months; (3) Severe diabetic complications (diabetic ketoacidosis, severe diabetic peripheral neuropathy, etc.); (4) Research subjects with severe primary diseases, including but not limited to severe diarrhea, uncontrolled hypertension (systolic blood pressure =180mmHg and/or diastolic blood pressure =110mmHg), severe cardiopulmonary insufficiency, and severe liver and kidney function impairment (ALT and AST greater than twice the upper limit of normal values) Or Cr greater than the upper limit of the normal value, severe lung diseases (uncontrolled asthma, acute respiratory failure, and severe hypoxemia, etc.), acute and chronic infections, malignant tumors, etc. (5) Specific bleeding history, or bleeding history caused by taking warfarin; (6) Those suffering from severe mental illnesses (such as major depression, schizophrenia, etc.); (7) Pregnant women, lactating women or women of childbearing age who have not taken effective contraceptive measures; (8) Research subjects who have participated in any other clinical research or taken its investigational drugs within the past month; (9) Those who are known or suspected of being allergic to the drug in this study or have an allergic constitution (which may manifest as rash, fever, breathing difficulties or even anaphylactic shock); (10) Those with dysphagia who cannot take medicine; (11) The researchers consider the candidates unsuitable for selection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Homeostatic Model Assessment of Insulin Resistance;Seattle Angina Questionnaiire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency and duration of angina pectoris attacks;Fasting Blood Glucose;Insulin;Hemoglobin A1c;GlycatedSerumProteins;Total Cholesterol;Triglyceride;Low-Density Lipoprotein;TCM symptom score; | — |
Countries
China
Contacts
Public ContactXie Yanming
Institute Of Basic Research In Clinical MedicineChina Academy Of Chinese Medical Sciences
Outcome results
None listed