Infertility due to diminished ovarian reserve
Conditions
Interventions
Test group:3-month Zuogui Pill + Elevit
control group:3-month Zuogui Pill Placebo + Elevit
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 42 Years
Inclusion criteria
Inclusion criteria: 1.Conform to the diagnostic criteria of DOR and kidney deficiency syndrome ; the diagnostic criteria of DOR were formulated according to the Bologna Consensus and ' Obstetrics and Gynecology ' ( Ninth Edition ), ' Expert Consensus on Clinical Diagnosis and Treatment of Decreased Ovarian Reserve ' ( 2022 ), ' Guidelines for Diagnosis and Treatment of Decreased Ovarian Reserve with Integrated Traditional Chinese and Western Medicine ' ( Chinese Society of Integrated Traditional Chinese and Western Medicine, Chinese Society of Traditional Chinese Medicine, Chinese Medical Association, 2023 ) : ( 1 ) 10 U / L 20 and = 42 years old, have fertility needs ; 4.Voluntary signing of informed consent
Exclusion criteria
Exclusion criteria: (1) Other clear causes of infertility (e.g., fallopian tube obstruction, endometriosis stage III-IV); (2) Severe gynecological diseases, DOR caused by prior ovarian surgery, radiotherapy/chemotherapy, or chromosomal abnormalities; (3) Severe systemic diseases (e.g., uncontrolled hypertension, diabetes) or malignancies; (4) Use of hormonal medications or TCM treatments within 3 months; (5) Patients with predominant Kidney Yang deficiency; (6) Failure to undergo IVF-ET within 3 months after TCM treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-Müllerian Hormone (AMH);Total Oocytes Retrieved Through Assisted Reproductive Technology; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex Hormone Levels;Antral Follicle Count (AFC);High-Quality Embryo Rate;Clinical Pregnancy Rate;Biochemical Pregnancy Rate;TCM syndrome score; | — |
Countries
China
Contacts
Public ContactLi Dong
Peking University Third Hospital
Outcome results
None listed