Perimenopausal mild depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women aged 40 to 60; 2. Within one year of menopause or with a history of menstrual irregularities, presenting typical symptoms of hot flashes and night sweats, which may be accompanied by irritability, palpitations, insomnia, emotional disturbances, memory decline, aching in the lower back and legs, and dyspareunia. 3. Exhibits at least two of the following symptoms: (1) Depressed mood, present for most of the day, nearly every day, largely unaffected by circumstances, lasting at least two weeks; (2) Lack of energy or excessive fatigue; (3) Loss of interest or pleasure in activities that were previously enjoyable 4. Hamilton Depression Rating Scale (HAMD-17) total score =8 and <17; 5. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1: Assessing suicidal tendencies using the Beck Depression Inventory; 2: Have taken estrogen or selective serotonin reuptake inhibitors within the past 4 weeks; 3: Combined hypertension, renal failure, and other malignant diseases; 4: Implant a pacemaker.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale 17-item (HAMD-17) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Kupperman Index;Menopause-specific Quality of Life questionnaire;Self-Rating Depression Scale;Self-Rating Anxiety Scale;Heart Rate Variability; | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Chinese Medicine