Knee osteoarthritis
Conditions
Interventions
Treatment group:External application of heated Quxie Lijie formula combined with exercise rehabilitation training
Control Group:External application of heated Quxie Lijie formula
Sponsors
Aviation General Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged 50-70 years, regardless of gender. (2) Meets diagnostic criteria from the 2024 Chinese Osteoarthritis Diagnosis and Treatment Guidelines. (3) Conforms to cold-dampness obstruction syndrome criteria in the 2021 Integrated Diagnosis and Treatment Guidelines for Osteoarthritis. (4) Drug washout: Patients using NSAIDs require 2-week discontinuation before enrollment; those using Adequan or corticosteroids require 1-month discontinuation. (5) Voluntary informed consent.
Exclusion criteria
Exclusion criteria: (1) Age 70 years. (2) Allergy or intolerance to experimental medications. (3) Severe primary diseases of cardiovascular, cerebrovascular, hepatic, renal or hematopoietic systems; mental disorders; epilepsy; photosensitive diseases; intracranial implants or unresolved head trauma; severe obesity (BMI=35 kg/m²); severe osteoporosis. (4) Moderate-severe osteoarthritis (K&L grade III-IV). (5) Previous knee replacement, ligament reconstruction or arthroscopic surgery; recent (within 6 months) lower limb fracture or surgery. (6) Inability to complete assessments. (7) Non-KOA related balance disorders (e.g., vestibular dysfunction, spinal lesions). (8) Refusal to sign informed consent.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Lyshom Knee Rsting System;TCM Symptom Efficacy Evaluation;Isokinetic Dynamometry;Balance Function Assessment;Cerebral Cortex Activation Pattern Assessment; | — |
Primary
| Measure | Time frame |
|---|---|
| Arthritis Pain Assessment (VAS);Western Ontario and McMaster Osteoarthritis Index; | — |
Countries
China
Contacts
Public ContactWang Wanru
Aviation General Hospital
Outcome results
None listed