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The efficacy and mechanism of moxibustion at different temperatures in treating yang deficiency type depression

The efficacy and mechanism of moxibustion at different temperatures in treating yang deficiency type depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000126
Enrollment
Unknown
Registered
2026-01-22
Start date
2024-12-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nosocomia

Interventions

Simple drug group:After breakfast Escitalopram was taken orally 10mg once a day for 4 weeks.
Moxibustion group at 45?:After breakfast, escitalopram was taken orally, 10mg, once a day, Dazhi, Xinshu, Ganshu and Pishu were selected for moxibustion at each point for 15min, and moxibustion was ap
Moxibustion group at 38?:After breakfast, Escitalopram was taken orally,10mg, once a day, Dazhi, Xinshu, Ganshu and Pishu were selected for moxibustion at each point for 15min, and moxibustion was app

Sponsors

Zhongda Hospital affiliated to Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Only those who meet all of the following 7 criteria will be included: (1) Those who meet the diagnostic criteria for depression in Western medicine; (2) Those who meet the diagnostic criteria for Yin deficiency in Liver Disease in traditional Chinese medicine; (3) Subjects with HAMD-17 total score of less than 17 and no more than 24 for mild to moderate depression; (4) Subjects aged between 18 and 65 with no gender restrictions; (5) Those who are conscious and have no intellectual disabilities and can cooperate with treatment; (6) Subjects who voluntarily participate in this study; (7) Those who sign the informed consent form.

Exclusion criteria

Exclusion criteria: Anyone who meets any of the following criteria will be excluded from the study: Severe depression; Patients with severe organic diseases; Alcohol or drug addicts; Patients who have received other depression-related treatments within the past two weeks; Patients who cannot take medication as prescribed;6) Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
TCM syndrome score scale;Hamilton Depression Scale -17 items;

Secondary

MeasureTime frame
IL-6;Brain-derived neurotrophic factor;miRNA-16;CRP;5-HT;

Countries

China

Contacts

Public Contactwang guiying

The Affiliated Zhongda Hospital of Southeast University

guiyingw@163.com13505175239

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 7, 2026