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Evaluation of the therapeutic efficacy and clinical translation of a comprehensive traditional Chinese medicine treatment plan for degenerative lumbar spondylolisthesis--A multicenter cohort study

Evaluation of the therapeutic efficacy and clinical translation of a comprehensive traditional Chinese medicine treatment plan for degenerative lumbar spondylolisthesis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000118
Enrollment
Unknown
Registered
2026-01-22
Start date
2026-01-26
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Degenerative lumbar spondylolisthesis

Interventions

Cohort study: Traditional Chinese Medicine Treatment:Oral Chinese herbal decoctions and/or manual therapy
Cohort study: Western medicine treatment:Oral Celecoxib Capsules Combined with Waist Fixation
Cohort study: integrated Chinese and Western medicine treatment corhot:Oral Chinese herbal decoctions and/or manual therapy combined with oral celecoxib capsules for waist circumference fixation

Sponsors

The First Affiliated Hospital of Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: In order to be included in this experiment, participants must: 1) Simultaneously meeting the diagnostic criteria for chronic back pain in traditional Chinese medicine and degenerative lumbar spondylolisthesis in Western medicine; 2) Age = 18 years old, male or female not limited; 3) Lower back pain VAS score = 4 points; 4) I voluntarily participate in this experiment and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Participants who fall under any of the following circumstances will be excluded from this trial: 1) Lumbar spondylolisthesis caused by congenital spinal lesions, as well as developmental dysplasia, isthmus, traumatic, and pathological lumbar spondylolisthesis; 2) Slippery caused by spinal infections, traumatic fractures, tumors, tuberculosis, and osteoporosis; 3) Patients with other serious primary diseases and complications in internal medicine, such as severe liver or kidney disease, severe heart disease or poorly controlled hypertension, diabetes, severe gastrointestinal diseases or digestive system problems; 4) Individuals who have undergone lumbar surgery or other major surgeries; 5) Patients with severe skin damage or skin diseases in the manipulation area; 6) Contraindications for manipulation: such as obvious neurological dysfunction or progressive aggravation; The study suggests that there are other patients who are not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale;

Secondary

MeasureTime frame
Oswestry disability index ;36-item Short-Form;Efficient;the frequency of attacks and the duration of each episode;X-ray of lumbar;Adverse event;Safety indicators (three routine liver and kidney function body temperature respiration heart rate blood pressure electrocardiogram);Lumbar spine mobility;Gait feature monitoring;

Countries

China

Contacts

Public ContactChengliang Wu

Zhejiang Chinese Medical University

wcl@zcmu.edu.cn13175007769

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 7, 2026