Colorectal cancer
Conditions
Interventions
Intervention group:Intervention of Xiaochaihu Decoction formula granules
control group:Intervention of Chinese herbal placebo formula granules
Sponsors
The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with colorectal cancer through pathology or cytology. 2) Patients with TNM staging of stage II, III, and IV; 3) Age range of 18-80 years old, expected survival period>6 months; 4) KPS = 60 points; 5) Voluntarily participate and sign an informed consent form, and cooperate with the follow-up. 6) If any of the following conditions are met: A. CPSS-14 Chinese Stress Perception Scale = 29 points; B. PHQ-9 Depression Screening Scale = 5 points; C. GAD-7 Self Rating Anxiety Scale = 5 points; D. The Traditional Chinese Medicine Syndrome Scale determines liver depression and spleen deficiency, as well as liver depression and qi stagnation.
Exclusion criteria
Exclusion criteria: 1) Merge primary tumors from other parts; 2) There are non tumor related serious diseases and functional disorders, active cerebrovascular disease, uncontrolled infections, and metabolic diseases in major organs such as the liver, kidneys, and heart; 3) Those who have received treatment with anti anxiety, depression, and antipsychotic drugs within six months.; 4) Individuals who are allergic to known components of traditional Chinese medicine used in the study; 5) Pregnant women, lactating women, and mentally ill patients; 6) Those who are currently participating or have participated in other drug clinical trials within the past 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Quality of life;Traditional Chinese Medicine Syndrome Indicators;Immune function;The degree of emotional disorders in patients;Serum neurotransmitter; | — |
Countries
China
Contacts
Public ContactYan Wang
The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Outcome results
None listed