Perianal abscess
Conditions
Interventions
Treatment group:In addition to the control group, the experimental group took Tuoli Disinfecting Powder formula (adjusted as needed) once daily.
Control Group:Intravenous antibiotic infusion for 3 days + sitz bath with steaming using 500mL of warm water and, twice daily + Relfenore-soaked gauze for dressing changes, once daily.
Sponsors
Inner Mongolia Autonomous Region Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
19 Years to 56 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the following diagnostic criteria and undergo one-time radical surgery for perianal abscess: Low-position perianal abscess: Occurs below the levator ani muscle, including perianal subcutaneous abscess, ischiorectal fossa abscess, posterior anal canal abscess, and low-position horseshoe abscess. Clinically, it presents with local skin redness, swelling, heat, and pain, with a fluctuant sensation upon palpation, and most patients have no significant systemic symptoms. High-position perianal abscess: Occurs above the levator ani muscle, including pelvic rectal space abscess, posterior rectal space abscess, submucosal rectal abscess, and high-position horseshoe abscess. Clinically, some patients may have systemic symptoms such as fever and chills. Blood tests show increased white blood cell and neutrophil counts. Digital rectal examination may reveal tenderness and protrusion of the rectal wall, and pelvic CT or MRI can confirm the location of the abscess. Postoperative perianal abscess: After surgery, pus is discharged, pain is alleviated, the incision color is not fresh, the surface is uneven, and palpation shows no heat or slight heat, with mild tenderness and slow healing. Incisions after low-position perianal abscess surgery are often superficial, while those after high-position perianal abscess surgery are often large and deep. Postoperative anal boil: Local symptoms: After pus discharge, the local skin temperature of the wound is not hot or slightly hot, the tissue is hard upon palpation or the fluctuant sensation is reduced, necrotic tissue is difficult to shed, new tissue does not grow, and the wound does not heal for a long time. Systemic symptoms: Normal or low-grade fever, fatigue, sweating, constipation, yellowish or dark urine, or difficulty urinating. Qi and blood deficiency with residual toxicity: Constitutionally weak, fatigue, and body softness; the lesion is flat, with dark purple or dull skin color, no heat or slight heat upon palpation, mild tenderness, thin pus after surgery, wound surface grayish-white or dark red, no growth of new tissue, and slow wound healing; mental fatigue, lack of vitality, pale complexion, abdominal distension, loose stools, poor appetite, pale or dark tongue, thin white, yellow, or thick white coating, and a deep, fine, rapid, slow, wiry, orpulse. (2) Patients aged =18 and =60 years, regardless of gender; (3) Patients with no history of anal surgery and no abnormal anal function or morphology; (4) Patients without contraindications to surgery; (5) Patients who agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with combined cardiovascular, cerebrovascular, liver, kidney, hematopoietic, and endocrine system diseases, as well as mental illnesses; (2) Patients with inflammatory bowel diseases such as Crohn's disease and ulcerative colitis; (3) Patients with other anorectal diseases such as anal and rectal tumors and perianal skin diseases; (4) Patients with perianal abscess caused by trauma; (5) Patients with infectious diseases; (6) Patients allergic to the components of Chinese herbal medicine; (7) Pregnant and breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing rate;Interleukin-1 beta;Interleukin-6;Tumor Necrosis Factor-alpha;Phosphorylated Signal Transducer and Activator of Transcription 3;Vascular Endothelial Growth Factor protein;Vascular Endothelial Growth Factor mRNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound pain score;Exudate Exudation Volume Scoring; | — |
Countries
China
Contacts
Public Contactplateau
Inner Mongolia Autonomous Region Traditional Chinese Medicine Hospital
Outcome results
None listed