Coronary Heart Disease
Conditions
Interventions
Tanhuo decoction Group:Standard Western Treatment and Tanhuo decoction
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: **Inclusion criteria:** 1. Patients with acute coronary syndrome who achieve hemodynamic stability within 24 hours after treatment; 2. A prior confirmed diagnosis of ischemic cerebrovascular disease, or =50% intracranial or extracranial arterial stenosis confirmed after admission by carotid ultrasonography and cerebrovascular ultrasonography; 3. Presence of manifestations consistent with the phlegm–heat syndrome, assessed based on tongue body, tongue coating, stool, mental state, facial appearance, breathing, presence/absence of fever, pulse characteristics, oral sensation, and urine. A weighted scoring system is applied to each item, and a total score =7 indicates phlegm–heat syndrome; 4. Age =60 years; 5. Either sex; 6. Provision of written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with persistent hemodynamic instability for >24 hours or hypotension related to acute coronary syndrome (blood pressure 5× the upper limit of normal, or creatinine clearance <30 mL/min/1.73 m²; 5. History of bronchial asthma; 6. Platelet count <80 × 10^9/L, or anemia (hemoglobin =100 g/L); 7. Contraindications to or allergy/hypersensitivity to aspirin, clopidogrel, ticagrelor, or statins; 8. History of malignancy; 9. Allergy to any components of traditional Chinese medicine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| White blood cell count;Neutrophil count;High-sensitivity C-reactive protein;Interleukin-6; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of major adverse cardiovascular and cerebrovascular events; | — |
Countries
China
Contacts
Public ContactXia Jinggang
Xuanwu Hospital, Capital Medical University
Outcome results
None listed