Post-stroke cognitive impairment
Conditions
Interventions
Routine Cognitive Rehabilitation Therapy Group:Cognitive training is conducted for individuals with varying degrees of cognitive impairment, targeting specific cognitive domains such as attention, mem
taVNS-train Synchronized Therapy Group:Concurrent with routine rehabilitation training, taVNS intervention is implemented. Based on the patients degree of cognitive impairment, targeted methods are se
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: The diagnostic criteria are based on the 2017 Expert Consensus on the Management of Post-stroke Cognitive Impairment and the "Chinese Guidelines for the Prevention and Treatment of Cerebrovascular Diseases (2021 Edition)": 1. Patients diagnosed with cerebral infarction via MRI or CT, or intracerebral hemorrhage, or lacunar infarction; 2. Presence of PSCI (diagnostic criteria refer to the 2017 Expert Consensus on the Management of Post-stroke Cognitive Impairment), with MMSE scores =17 for illiterate individuals, =20 for primary school graduates, and =24 for those with middle school education or above; or MoCA scores <26; 3. Age between 20 and 85 years; 4. Right-handed; 5. Educational level of primary school or above; 6. Last episode within 24 months; 7. Voluntarily participating in this research project and signing the informed consent form.
Exclusion criteria
Exclusion criteria: a. Mood or mental disorders, visual and auditory impairments, severe heart, liver, or kidney diseases, or infectious diseases, Parkinson's disease, epilepsy, or a first-degree relative with a history of idiopathic epilepsy, and those using epileptogenic drugs; b. Skull defects, individuals with pacemakers, or those with metal implants in the body who are unsuitable for MRI; c. Those with pre-existing damage to the musculoskeletal system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental State Examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale;MRI Data; | — |
Countries
China
Contacts
Public ContactZhao Jingjun
Peking University People's Hospital?
Outcome results
None listed