Postoperative nausea and vomiting
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 45 years old; 2. Nulliparas or multiparas; 3. Gestational age of 37 to 42 weeks; 4. Singleton pregnancy; 5. American Society of Anesthesiologists Physical Status Classification II-III; 6. Scheduled for cesarean section under subarachnoid anesthesia
Exclusion criteria
Exclusion criteria: 1. Allergy to morphine, local anesthetics and other drugs involved in the study; 2. With severe hepatic and renal dysfunction, cardiovascular diseases, endocrine system diseases, etc.; 3. Facial skin infections, lesions or skin diseases, making them unsuitable for buccal acupuncture manipulation; 4. History of mental illness or cognitive impairment, unable to cooperate with pain assessment and relevant questionnaires; 5. Preoperative comorbidity of motion sickness, or use of antiemetics, analgesics or other drugs that may affect the study results within 24 hours before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of postoperative nausea and vomiting episodes;Severity of postoperative nausea and vomiting;Incidence of postoperative pruritus;Severity of postoperative pruritus;Severity of postoperative resting pain;Severity of postoperative moving pain;Incidence of urinary retention;Time to first postoperative flatus;Time to first colostrum secretion;Postoperative plasma C-reactive protein (CRP) level;Postoperative plasma interleukin-6 level;Postoperative plasma tumor necrosis factor-a level;Postoperative cortisol level;Postoperative ß-endorphin level;Severity of postoperative anxiety and depression;Postoperative sleep quality;Postoperative quality of recovery; | — |
Countries
China
Contacts
People's Liberation Army (PLA) Northern Theater Command General Hospital