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A Pragmatic Randomized Controlled Clinical Trial Study on the Efficacy of an Optimized Protocol Based on Traditional Auricular Acupuncture Techniques in Improving Anorexia in Patients with Advanced Malignant Tumors

A Pragmatic Randomized Controlled Clinical Trial Study on the Efficacy of an Optimized Protocol Based on Traditional Auricular Acupuncture Techniques in Improving Anorexia in Patients with Advanced Malignant Tumors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000049
Enrollment
Unknown
Registered
2026-01-10
Start date
2026-01-25
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer anorexia

Interventions

Protocol I Treatment Group:High-frequency electroacupuncture stimulation combined with ear acupoint pressing.
Protocol II Treatment Group:Low-frequency electroacupuncture needle combined with ear acupoint seed pressing

Sponsors

Tianjin Yellow River Hospital (Tianjin Sports Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Age = 18, gender; 2. Confirmed by pathology as malignant tumor or confirmed by imaging or pathology as advanced malignant tumor (with distant metastasis and no surgical opportunity); 3. Meets the diagnostic criteria for moderate to severe cancer-related anorexia (appetite VAS score > 6 points); 4. KPS score = 60 points; 5. Patients currently receiving targeted therapy, immunotherapy, or chemotherapy are eligible for inclusion; 6. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Those with anorexia not caused by tumors or their related factors; 2. Individuals assessed by a physician to have a risk of venous thrombosis; 3. Presence of large amounts of pleural or peritoneal effusion; 4. Skin injuries or breaks on the body surface that prevent acceptance of electroacupuncture therapy; 5. Expected survival period of no more than 3 months and deemed unsuitable for participation in the study after assessment by the attending physician.

Design outcomes

Primary

MeasureTime frame
Appetite Quantitative Assessment Index (VAS);

Secondary

MeasureTime frame
Weight;TCM Spleen Deficiency Scale;Functional Assessment Scale for Anorexia and Cachexia in Cancer Patients;Massachusetts General Hospital Acupuncture Sensation Scale;Karnofsky Performance Status Scale;Quality of Life Assessment;Gastric Electrogastrography;Patient-Subjective Global Nutritional Assessment ;

Countries

China

Contacts

Public ContactZhao Tianyi

School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine

zhaotianyi89@126.com13820642091

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 7, 2026