pulmonary infection
Conditions
Interventions
control group:Only undergo conventional Western medical treatment without electroacupuncture intervention.
Electroacupuncture intervention group:Undergo basic Western medical treatment and receive electroacupuncture intervention.
Sponsors
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1)Age 18 to 75 years, gender unspecified; 2) Confirmed by CT or MRI as traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, or ischemic stroke; 3) Meets criteria for severe acute brain injury (GCS =12 or NIHSS =15); 4) Time from onset to enrollment =24 hours; 5) Informed consent signed by the subject or legal representative.
Exclusion criteria
Exclusion criteria: 1. Patients who have been diagnosed with pulmonary infection before admission; 2. Coma caused by tumors, infectious diseases, cardiac arrest, or hypoglycemia; 3. Patients who have undergone endotracheal intubation, subglottic secretion drainage, or mechanical ventilation via tracheostomy; 4. Patients with pulmonary tuberculosis, pulmonary fibrosis, chronic obstructive pulmonary disease (COPD), bronchial asthma, chronic bronchitis, or interstitial lung diseases; 5. Patients with severe heart, liver, or kidney failure, malignant tumors, or other autoimmune diseases; 6. Patients with a history of severe infection or sepsis within the past month; 7. Patients who have used antibiotics or glucocorticoids within the past week; 8. Patients with lower limb trauma or deep vein thrombosis; skin infection, ulcer, or severe coagulation disorders at the acupuncture site; 9. Patients with implanted pacemakers or other active cardiac electronic devices that may be affected by electroacupuncture; 10. Patients participating in other clinical studies; 11. Lactating or pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of pulmonary infection within 7 days.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of Infection (days);Percentage of new antibiotic use within 7 days / Duration;The proportion requiring mechanical ventilation within 7 days.;ICU/Hospitalization Days;Neurological evaluation;Inflammation/Immune-Related Laboratory Indicators; | — |
Countries
China
Contacts
Public ContactGuiwei Li
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed