Sepsis-Associated Acute Respiratory Distress Syndrome
Conditions
Interventions
The control group.:Conventional medical treatment will be administered, including but not limited to providing respiratory support based on the patients respiratory function, implementing protective l
The intervention group.:Based on the treatment in the control group, the Xuanfei Tiaojiao Decoction will be administered. The decoction will be prepared by the hospital's pharmacy, divided into two ba
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1)Definitive diagnosis of sepsis-induced ARDS; 2)Disease severity classified as mild to moderate (P/F ratio > 100); 3)Meeting the Traditional Chinese Medicine syndrome differentiation criteria for phlegm-heat accumulation in the bowels; 4)Age between 18 and 85 years; 5)Obtained informed consent signed by the patient or their authorized representative.
Exclusion criteria
Exclusion criteria: 1)Patients with uncontrolled gastrointestinal bleeding, intestinal obstruction, gastrointestinal intolerance requiring fasting, or inability to receive enteral nutrition; 2)Participation in other clinical trials within the past three months or currently enrolled in other trials; 3)Suspected or confirmed allergy to the study medication; 4)Refusal of study procedures or refusal of active treatment; 5)Clinically judged to be expected to die within 48 hours; 6)Pregnant or breastfeeding women; 7)Patients with major diseases such as malignant tumors, history of organ transplantation, autoimmune diseases, or severe psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-Day Mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete Blood Count;Tumor Necrosis Factor-a;Arterial Blood Gas Analysis;Procalcitonin;C-Reactive Protein;Interleukin-6;SOFA;APACHE II;Gastrointestinal Dysfunction Score;Abdominal Circumference;Borborygmus;The Rate of Mechanical Ventilation;The Duration of Mechanical Ventilation;Length Of ICU Stay;The Mortality in ICU;TCM syndrome scores; | — |
Countries
China
Contacts
Public ContactHan Yun
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed