Colorectal cancer
Conditions
Sponsors
Xuzhou First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with elective laparoscopic colorectal tumor surgery; 2. Aged 18 to 75 years; 3. American Society of Anesthesiologists (ASA) grades I to III; 4. BMI 18.5-28kg/m^2; 5. Preoperative clinical tumor TNM staging: cTis-3N0-1M0 (refer to AJCC/UICC 9th edition TNM staging).
Exclusion criteria
Exclusion criteria: 1. ICFS-10 Perioperative Fatigue Evaluation Scale score > 24 points; 2. PSQI Pittsburgh Sleep Quality Index score > 7 points; 3. Sleep apnea syndrome, or moderate or higher snoring; 4. Severe sinus bradycardia (heart rate 38.5°C) or clinical evidence of infection (hematological, radiological, and/or microbiological) preoperatively; 12. Patients sharing a residence or with critically ill patients or with more than 3 people.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue index;Heart rate variability (HRV);Sleep Index;Nuclear factor erythroid 2-related factor 2;Heme oxygenase-1 ;Superoxide Dismutase;Glutathione peroxidase;cortisol;Interleukin-6;Tumor Necrosis Factor-alpha;C-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Identity Consequences Fatigue Scale;Pittsburgh Sleep Quality Index score;Visual Analogue Scale Score;Intraoperative blood pressure;Operation time;Intraoperative blood loss;Time of first air exhaust after operation;Adverse events and medication;Hospital stay; | — |
Countries
China
Contacts
Public ContactYang Weibin
Xuzhou First People's Hospital
Outcome results
None listed