Knee osteoarthritis
Conditions
Interventions
Experimental Group:Basic treatment + Oral non-steroidal anti-inflammatory and analgesic drugs + Eurya emarginata decoction for fumigation and washing
Control Group:Basic treatment plus oral nonsteroidal anti-inflammatory and analgesic drugs.
Sponsors
Yellow River Sanmenxia Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Patients who meet the diagnostic criteria for knee osteoarthritis (unilateral or bilateral); 2) Patients who meet the diagnostic criteria for cold-damp obstruction syndrome in traditional Chinese medicine for knee osteoarthritis; 3) Patients aged between 50-70 years, with no gender restrictions; 4) Patients with a disease duration of knee osteoarthritis = 3 months; 5) Knee joint X-ray K-L grading belongs to Grade I-II; 6) The staging of knee osteoarthritis belongs to the initial or early stage; 7) Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) score < 12 points; 8) Visual Analog Scale (VAS) score between 3 and 5 points (inclusive); 9) Signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Those who have taken Chinese herbal decoctions, traditional Chinese medicine preparations, or other Western medications for the treatment of knee osteoarthritis within the past week; 2) Individuals with an allergy to sulfonamide drugs; 3) Patients with concurrent knee joint tumors, tuberculosis, rheumatism, rheumatoid arthritis, or gouty arthritis; 4) Patients who have undergone knee joint replacement surgery; 5) Pregnant women, those planning pregnancy, or breastfeeding women; 6) Patients with severe underlying conditions of the cardiovascular, cerebrovascular, or hematopoietic systems, mental illness, malignant tumors, or impaired liver or kidney function; 7) Individuals currently participating in other clinical trials that may affect the evaluation of this study's results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The response rate of the Visual Analogue Scale for Pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index Total Score;Western Ontario and McMaster Universities Osteoarthritis Index Subscale Score;Quality of Life Score (SF-12);Traditional Chinese Medicine syndrome score; | — |
Countries
China
Contacts
Public ContactWang Yaosheng
Yellow River Sanmenxia Hospital
Outcome results
None listed