Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Experimental Group:Yihuo Huatan Formula Instant decoction
Control Group:Yihuo Huatan Formula Instant placebo
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: **Study 1 Inclusion Criteria:** 1. Presence of risk factors for COPD. 2. History of chronic bronchitis and/or emphysema, with at least one of the following symptoms: - Cough; - Sputum production; - Dyspnea. 3. Pulmonary function test results meeting the following criteria: - FEV1/FVC = 70%, and - FEV1% < 80%. 4. Consistent with the syndrome of qi deficiency, blood stasis, and phlegm turbidity. 5. Age between 18 and 65 years. 6. Voluntary participation in the study and signing of the informed consent form. **Study 2 Inclusion Criteria:** 1. Age between 40 and 80 years. 2. In the stable phase of COPD. 3. Traditional Chinese medicine diagnosis corresponds to Qi deficiency, blood stasis, and phlegm-dampness syndrome. 4. Voluntary participation in the study and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Women in pregnancy, planning pregnancy, or lactation; (2) Patients with dementia or various mental illnesses; (3) Patients suffering from other conditions that cause chronic cough, phlegm production, or breathing difficulties; (4) Patients with comorbidities such as tumors, severe cardiovascular diseases, severe liver or kidney diseases, or severe hematological disorders; (5) Individuals currently participating in other clinical trials of medications; (6) Patients allergic to the intervention drugs; (7) Patients deemed unsuitable for participation in this clinical trial by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine symptom efficacy;Annual acute exacerbation frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Scoring;Pulmonary Function;COPD Assessment Test;modified Medical Research Council Dyspnea Scale;Clinical COPD Questionnaire;Saint George's Respiratory Questionnaire;Hospital Anxiety and Depression Scale;Incidence rate of COPD;First acute exacerbation time;The incidence rate of acute respiratory infections;6-minute walking distance; | — |
Countries
China
Contacts
Public ContactBing Mao
West China Hospital Of Sichuan University
Outcome results
None listed