Type 2 diabetic nephropathy
Conditions
Interventions
Control Group:Lifestyle and dietary interventions
control blood glucose, blood pressure, and blood lipid levels.
Treatment group:Administer Danggui Shaoyao San in addition to the control group (adjustable according to symptoms).
Sponsors
Hebei Medical University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 75 years (inclusive of 18 and 75 years); (2) Meet the diagnostic criteria and staging for the aforementioned type 2 diabetic nephropathy; (3) Meet the diagnostic criteria, staging, and pattern identification for the aforementioned traditional Chinese medicine diagnosis of xiaoke disease nephropathy.
Exclusion criteria
Exclusion criteria: Any of the following conditions apply: (1) kidney diseases caused by other reasons, such as hypertensive nephropathy, lupus nephritis, IgA nephropathy, etc.; (2) acute complications of diabetes in the past 3 months, such as diabetic ketoacidosis and hyperglycemic hyperosmolar coma, etc.; (3) severe cardiovascular, neurological, hematological, or psychiatric diseases; (4) pregnant, peripartum, or breastfeeding women; (5) participation in other clinical trials within 4 weeks prior to the start of treatment; (6) contraindications or allergies to this medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Creatinine (SCr);Blood Urea Nitrogen (BUN);Estimated Glomerular Filtration Rate (eGFR);Fasting Blood Glucose (FBG);Glycated Hemoglobin (HbA1c);Hypoxia-Inducible Factor 1-alpha; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine Albumin-to-Creatinine Ratio (UACR);Urine Microalbumin (ALB);Total Cholesterol (TC);Triglyceride (TG);Low-Density Lipoprotein Cholesterol (LDL-C);High-Density Lipoprotein Cholesterol (HDL-C);8-hydroxydeoxyguanosine (8-OHdG);Malondialdehyde (MDA);Superoxide Dismutase (SOD);Plasma von Willebrand factor;Thrombomodulin;Plasminogen activator inhibitor-1;Fibrinogen;D-dimer (D-D);Thromboelastography Analysis;Traditional Chinese Medicine Syndrome Scoring; | — |
Countries
China
Contacts
Public ContactDong Wen
Hebei Medical University First Hospital
Outcome results
None listed