Colorectal Cancer
Conditions
Interventions
Intervention group:Chanling Granules
Control group:Placebo (5 % active Chanling granules)
Sponsors
The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: AI (1) Patients with a confirmed pathological diagnosis of colorectal cancer who met the diagnostic criteria for the aforementioned diseases; (2) Patients who had undergone radical resection for colorectal cancer and had completed adjuvant therapy within the preceding 3 months; or those within 6 months post-operation who had not received any postoperative adjuvant therapy; (3) TNM stage classified as high-risk stage II, stage III, or stage IVA (resectable synchronous metastases); (4) Age = 18 years; (5) Traditional Chinese medicine syndrome differentiation consistent with internal accumulation of stasis and toxin pattern; (6) No evidence of local recurrence or distant metastasis as confirmed by imaging; (7) Signed informed consent form.
Exclusion criteria
Exclusion criteria: (1) History of other malignant tumors within the past five years; (2) Patients with severe primary diseases such as cardiovascular and cerebrovascular diseases, hepatic or renal insufficiency, or hematopoietic system disorders; (3) Individuals allergic to any component of the Chinese herbal medicine; (4) Any unstable condition or factor that may compromise patient safety or study compliance, including but not limited to childbearing potential, pregnancy, lactation, or psychiatric disorders such as depression, manic-depressive disorder, obsessive-compulsive disorder, or schizophrenia; (5) Patients deemed by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2-year recurrence/metastasis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival;1-,3-year recurrence/metastasis rate;Quality of life; | — |
Countries
China
Contacts
Public ContactWenyu WU
The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Outcome results
None listed