Non-Arteritic Anterior Ischemic Optic Neuropathy
Conditions
Interventions
Experimental Group:Acupuncture combined with methylcobalamin tablets
Sponsors
Eye & ENT Hospital Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of NAION; 2. Those with a disease course of =3 months and stable condition; 3. Vision is between 0.05 and 0.5 (ETDRS visual acuity chart); 4. The MD value of the visual field is =-15 dB; 5. Age: 18-65 years old, gender not limited. 6. Informed consent and willingness to cooperate with follow-up visits.
Exclusion criteria
Exclusion criteria: 1. Those with other eye diseases affecting visual function, such as retinopathy, macular degeneration, etc. 2. Those with combined refractive media opacity (corneal leukoplakia, cataract, vitreous opacity) that affects ocular imaging or visual acuity assessment; 3. Those with chronic ocular surface diseases (conjunctivitis, keratitis, iridocyclitis); 4. Those with intraocular pressure exceeding the normal range (> 21 mmHg); 5. Those with a history of cerebrovascular accidents that affect visual pathways; 6. Hypertensive patients who are difficult to control through oral treatment (systolic blood pressure =180 mmHg and/or diastolic blood pressure =110 mmHg). 7. Those with concurrent malignant tumors and an expected lifespan of less than 2 years; 8. Those with concurrent infectious diseases such as syphilis, tuberculosis, and HIV; 9. Those taking optic neurotoxic drugs such as ethambutol and/or amiodarone hydrochloride; 10. Long-term smokers and heavy drinkers; 11. Women who are pregnant, planning to become pregnant or breastfeeding during the trial period; 12. Those who are unable to cooperate due to mental, intellectual or thinking abnormalities; 13. Those who have had active eye lesions or undergone eye surgery within the past six months; 14. Those with skin damage, ulcers, infections or scars at acupoints; 15. Subjects who are currently participating in other research projects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Deviation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Best-Corrected Visual Acuity(BCVA);Retinal Nerve Fiber Layer Thickness;Macular Ganglion Cell Complex Thickness;Visual Evoked Potential;Optic disc blood flow density;Vision-Related Quality of Life Score;Traditional Chinese Medicine Syndrome Scoring; | — |
Countries
China
Contacts
Public ContactZhou Xingtao
Eye & ENT Hospital Fudan University
Outcome results
None listed