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Study on the Changes of Tongue Manifestations in Lung Cancer Patients Undergoing Chemotherapy and Its Correlation with Tongue Coating Microbiota and Metabolic Indicators

Study on the Changes of Tongue Manifestations in Lung Cancer Patients Undergoing Chemotherapy and Its Correlation with Tongue Coating Microbiota and Metabolic Indicators

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025002578
Enrollment
Unknown
Registered
2025-12-29
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Observation group:Exposure: chemotherapy

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with a pathological diagnosis confirmed as non-small cell lung cancer; (2) Age =18 years old and =80 years old with no gender restriction; (3) Standardized chemotherapy regimens, including: chemotherapy; chemotherapy combined with anti-angiogenic therapy; chemotherapy combined with immunotherapy; (4) Patients who understand, agree to participate in this study, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Those who have used antibiotics or microbial agents in the past week; (2) Severe oral, gastrointestinal, and systemic infections; (3) Severe hepatic or renal dysfunction or other active severe systemic diseases; (4) Patients with multiple primary cancers; (5) Those who are uncooperative or unable to complete tongue image capture and sample collection; (6) Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
Oral microbiota;Tradisional Chinese Medicine tongue diagnosis;

Secondary

MeasureTime frame
Blood Routine;Urine Routine;Hepatic Function Test;Renal Function Test;Blood Glucose Levels;Lipid Profile;Tumor Markers;Inflammatory markers;Electrolyte Analysis;CT scan;PET-CT scan;MRI scan;General Information;

Countries

China

Contacts

Public ContactLing Xu

Department of Oncology I Yueyang Hospital of Integrated Traditional Chinese and Western Medicine

xulq67h@163.com15901903361

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026