Periodontits
Conditions
Interventions
Experimental Group:Nonsurgical periodontal therapy combined with Bushen Tianjing Yiqi recipe.
Control Group:Nonsurgical periodontal therapy
Sponsors
Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 35 and 65 years old (2)The clinical diagnosis is III/IV stage periodontitis (3)Patiens with kidney yang deficiency syndrome
Exclusion criteria
Exclusion criteria: (1) Received nonsurgical periodontal therapy within 3 months (2) Used antibiotics within the last month (3) Those with a history of diabetes and poor blood glucose control (glycated hemoglobin > 7.5%) (4) Those who smoke more than 10 cigarettes per day (5) Those with severe diseases such as heart, lung, hematopoietic system disorders, immune dysfunction, pregnancy, lactation period, or a history of surgery within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average changes of clinical loss attachment (at patient level ); | — |
Secondary
| Measure | Time frame |
|---|---|
| Average change value of probing depth (at patient level and tooth level);Changes of tooth mobility (at tooth level);Average changes of clinical loss attachment (at patient level );Changes in the score of syndromes;Changes of bleeding index in full-mouth probing (at patient level);Plaque index changes (at patient level);The microbial results of plaque and fecal samples;Metabolomic results of saliva samples; | — |
Countries
China
Contacts
Public ContactPei-hui DING
Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine
Outcome results
None listed