Premature Ovarian Insufficiency
Conditions
Interventions
Observation group:Electroacupuncture
Sponsors
The First Hospital of Hunan University of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) After hormone or B ultrasound diagnosis, in line with the above diagnostic criteria of Chinese and Western medicine ; 2) Accept acupuncture treatment and have a clear prescription of acupuncture ; 3) Patients who voluntarily participated in the clinical trial and cooperated with the examination and treatment, and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients who did not meet the above diagnostic criteria or inclusion criteria ; 2) Patients with heart, lung, liver, kidney, rheumatic immune, endocrine and other serious primary diseases or heart, lung, liver, kidney, brain failure and malignant tumors or precancerous lesions affected by sex hormones ; 3) Patients with ovarian dysfunction caused by ovarian, uterine and other related operations ; 4) Patients with congenital reproductive organ dysplasia or combined with polycystic ovary syndrome, hyperprolactinemia, hyperandrogenism, hypothyroidism, chronic adrenocortical dysfunction and other endocrine diseases affecting ovulation ; 5) Women in pregnancy or lactation ; 6) Those who were allergic to the drugs used in this study or who were suffering from other diseases or were receiving treatment that may have an impact on the indicators of this study ; 7) Patients with fainting or continuous damage of skin tissue at the acupuncture site, infection, coagulation dysfunction and skin allergy ; 8) Those who cannot cooperate with mental disorders, or cannot tolerate the blood or ultrasound detection and acupuncture treatment in the course of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum basic sex hormone levels;Anti-mullerian hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese medicine syndrome scores;CD4+ T cell level;CD8+ T cell level;AFC and Hemodynamics;Kupperman index;Changes in intestinal flora content;Olink targeted proteomics;Transcriptomics; | — |
Countries
China
Contacts
Public ContactZhang Wei
The First Hospital of Hunan University of Chinese Medicine
Outcome results
None listed