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Clinical study of ShexiangZhuifeng Analgesic Plaster combined with transcranial direct current stimulation in the treatment of knee osteoarthritis

Clinical study of ShexiangZhuifeng Analgesic Plaster combined with transcranial direct current stimulation in the treatment of knee osteoarthritis

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002557
Enrollment
Unknown
Registered
2025-12-27
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

ShexiangZhuifeng Analgesic Plaster combined with transcranial direct current stimulation group:ShexiangZhuifeng Analgesic Plaster combined with transcranial direct current stimulation
ShexiangZhuifeng Analgesic Plaster combined with sham transcranial direct current stimulation group:ShexiangZhuifeng Analgesic Plaster combined with sham transcranial direct current stimulation

Sponsors

Shanghai Seventh people's hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for KOA; (2) Age 50-75 years; (3) Disease duration exceeds 3 months; (4) Affected only on one knee joint; (5) Signed informed consent form.

Exclusion criteria

Exclusion criteria: (1) Anyone who has received any other treatment within the past month; (2) Anyone who is pregnant or breastfeeding; (3) Anyone with a neurological disorder (including neurodegenerative diseases, epilepsy, head injury); (4) Anyone with a tumor, tuberculosis, rheumatoid arthritis, gout, joint trauma, or any other chronic pain symptoms; (5) Anyone with a history of mental illness; (6) Anyone with a history of cardiovascular diseases such as pacemakers and coronary stents.

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale (VAS);

Secondary

MeasureTime frame
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Score;Resting-state EEG (power spectral density, functional connectivity);

Countries

China

Contacts

Public ContactLiming Jiang

Shanghai Seventh people's hospital

andy1487@126.com17621678676

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026