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A multicenter, randomized, controlled clinical study of detoxifying and skin-nourishing ointment in the treatment of acute radiation-induced skin injury

A multicenter, randomized, controlled clinical study of detoxifying and skin-nourishing ointment in the treatment of acute radiation-induced skin injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002552
Enrollment
Unknown
Registered
2025-12-27
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiation-induced skin injury

Interventions

Experimental group:Based on the patients original treatment plan, detoxifying and skin-nourishing ointment was applied externally. According to the lesion area, it was evenly applied to the radiation-
Control group:Use the patients original treatment plan and do not intervene with other drugs.

Sponsors

Jiangsu Hospital of Integrated Traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Patients with malignant tumors undergoing radiotherapy (2) Acute radiation-induced skin injury occurred, with RTOG grades I-III (3) Karnofsky score >60 points (4) Age: 18-85 years old, gender not limited, pre-survival period =3 months (5) Be conscious and have the ability to judge and evaluate one's own symptoms (6) The subjects and their families were informed and signed the consent form

Exclusion criteria

Exclusion criteria: (1) Patients with mental illness who cannot cooperate; (2) There is a purulent infection on the local skin, and the doctor determines that local medication cannot be applied. (3) Those who are currently participating in other research projects on radiation-induced skin damage.

Design outcomes

Primary

MeasureTime frame
The RTOG grade changes of radiation dermatitis after two weeks of medication;

Secondary

MeasureTime frame
The changes of RTOG grade of radiation dermatitis at other time points after medication;NRS Numerical Score for Pain;NRS Digital Score for Local skin Pruritus;Recovery time of skin lesions;Adverse reaction assessment;

Countries

China

Contacts

Public ContactGuoli Wei

Jiangsu Hospital of Integrated Traditional Chinese and Western Medicine

weiguoli1987@163.com+86 173 2700 6155

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026