Arrhythmia
Conditions
Interventions
Usual care group:Conventional medical treatment in Western medicine
Decoction Group:Sanshen Liansong Decoction
Granules Group:Sanshen Liansong Granules
Low-dose granules group:0.7 times the dose of Sanshen Liansong granules
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years and = 80 years gender not limited.; 2. Holter monitoring indicating premature beats with the diagnosis of premature beats meeting both Western and traditional Chinese medicine diagnostic criteria; 3. Willingness to undergo 12 weeks of medication treatment including but not limited to standardized drug therapy such as ß-blockers (unless contraindicated or intolerant the optimal treatment dose should be achieved); 4.Voluntary participation with understanding and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Potentially malignant or malignant arrhythmias such as atrial flutter and fibrillation; 2. Arrhythmias caused by severe valvular disease congenital heart disease pericardial disease and non-cardiac causes or premature beats due to the failure of important organs like the liver and kidneys; 3. Patients with serious primary diseases affecting the liver kidneys and hematological system renal dysfunction liver transaminases or alkaline phosphatase exceeding three times the normal upper limit blood creatinine > 2mg/dl (176.82umol/L) blood potassium > 5.5mmol/L; cancer patients those with severe neuroendocrine diseases and psychiatric patients and patients with clinically assessed expected survival time of less than 1 year due to malignant progressive diseases; 4. Patients with left ventricular outflow tract obstruction myocarditis aortic aneurysm dissecting aneurysm or unrepaired valvular heart disease causing significant hemodynamic changes; patients with cardiogenic shock uncontrollable malignant arrhythmias second-degree type II or higher sinoatrial or atrioventricular block without pacemaker treatment progressively worsening unstable angina or acute myocardial infarction; 5. Patients planning to undergo cardiac ablation surgery in the near future or those who have already received cardiac resynchronization therapy; 6. Individuals with allergies or known allergies to treatment medications; 7. Individuals who have participated in other drug clinical studies within the past month; 8. Pregnant or preparing for pregnancy and breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minnesota living with heart failure questionnaire;24-hour premature beat count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of palpitations and chest tightness;TCM Syndrome Points;ECG rhythms;Composite endpoint events; | — |
Countries
China
Contacts
Public ContactDing Banhan
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed