Sepsis
Conditions
Interventions
Observation group: Western medicine treatment + Tongfu Xiefei acupuncture group:On the basis of the treatment plan of the Western medicine group, acupuncture at Dazhui, bilateral Tianshu, Zusanli, and
Sham acupuncture at Dazhui acupoint + Western medicine treatment group:On the basis of the treatment plan of the western medicine group, sham acupuncture at Dazhui, bilateral Tianshu, Zusanli, and Sha
Sponsors
Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for sepsis-induced ARDS; (2) TCM syndrome differentiation being "pulmonary congestion and fu-organ excess type"; (3) Aged 18-80 years old; (4) Patients or their family members providing informed consent;
Exclusion criteria
Exclusion criteria: (1) Complicated with systemic anaphylaxis; (2) Complicated with severe structural lung diseases such as pneumothorax, bronchopleural fistula, and severe pulmonary fibrosis; (3) Advanced stage of malignant tumor; (4) Patients with clear acupuncture contraindications; (5) Previous immune system diseases; (6) Pregnancy and other situations where participation in clinical trials is not possible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequential Organ Failure Assessment Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-6, Tumor Necrosis Factor-a, Procalcitonin, C-reactive Protein, Fibroblast Growth Factor 21;Absolute counts of T lymphocyte subsets, including: CD3+T cells (total T cells), CD4+T cells (helper/inducer T cells), CD8+ T cells (cytotoxic T cells), and calculation of the CD4+/CD8+T cell ratio;TCM Syndrome Scoring Standard; | — |
Countries
China
Contacts
Public ContactZhiying Gao
Hunan University of Chinese Medicine
Outcome results
None listed