Allergic Rhinitis-Asthma Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Preclinical stage Meet the diagnostic criteria for AR and nasal disease; meet the diagnostic criteria for deficiency-cold of lung qi in traditional Chinese medicine; gender, age 18~75 years; asthmatic hyperresponsiveness positive (pulmonary function test/FeNO test); no other treatment used or treatment stopped for more than 2 weeks prior to enrollment; total nasal symptom score (TNSS) =4 points prior to enrollment; voluntarily participate in this clinical trial, voluntarily sign the informed consent, and willing to follow the study protocol.
Exclusion criteria
Exclusion criteria: (1) Patients who have progressed from AR to CARAS; (2) Patients with known allergies to any components of the drugs used in this study; (3) Patients with other nasal disorders, such as chronic rhinitis, paranasal sinusitis, nasal polyps, or deviated nasal septum; (4) Patients with notifiable infectious diseases, such as tuberculosis; (5) Patients with heart failure, moderate to severe hypertension, diabetes, other hematological diseases, or mental disorders who are unable to cooperate; (6) Patients in the pregnancy or lactation period, or those intending to become pregnant within the next 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of recurrent acute episodes of AR within 1 year;Improvement in symptom scores (TNSS and TNNSS scores); | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence rate of progression to CARAS within 1 year.; | — |
Countries
China
Contacts
Zhejiang Provincial Hospital of Traditional Chinese Medicine (Affiliated First Hospital of Zhejiang University of Traditional Chinese Medicine)