Multidrug-Resistant Perianal Abscesses
Conditions
Interventions
Combination group:Oral Tounongsan +EXternal liquid dressing
Liquid Dressing group:EXternal liquid dressing
Tounongsan group:Oral Tounongsan
Control group:EXternal Vaseline Gauze Strip
Sponsors
The Second Affiliated Hospital of Hunan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1). According to the "Twelfth Five-Year Plan" textbook "Science of Anorectal Diseases" published by Tsinghua University Press, the clinical diagnosis guidelines for perianal abscess, anal fistula and rectovaginal fistula of the American Society of Colon and Rectal Surgeons [1], and the three-dimensional color Doppler ultrasound diagnosis of the Second Affiliated Hospital of Hunan University of Chinese Medicine, patients meeting the diagnostic criteria for acute purulent perianal abscess at the low position and with multiple drug-resistant bacterial infection confirmed by pus bacterial culture and drug sensitivity test in the laboratory of the Second Affiliated Hospital of Hunan University of Chinese Medicine are included. (2). Patients aged between 18 and 60 years old. (3). Patients without clear surgical contraindications all undergo one-time radical surgery for perianal abscess. (4). Patients without blood diseases, diabetes, tuberculosis, inflammatory bowel disease or other major underlying diseases. (5). Patients who voluntarily participate in the clinical research and sign the informed consent form (see the attachment). (6). Patients without a history of perianal surgery. (7). Those with normal morphology and function of the anus.
Exclusion criteria
Exclusion criteria: (1). Those with complex or high-positioned perianal abscesses discovered during the operation; (2). Those with major underlying diseases such as heart, brain, liver or kidney diseases; (3). Those with other anorectal diseases: such as circumferential mixed hemorrhoids, anal fissures, malignant tumors in the anal area, severe perianal skin diseases, inflammatory bowel diseases, etc.; (4). Patients with mental or psychological disorders; (5). Those with infectious diseases such as AIDS, syphilis, or condyloma acuminatum; (6). Those with diseases that affect wound healing: such as diabetes, tuberculosis, malignant tumors, hyperthyroidism, malnutrition or heavy smokers; (7). Pregnant and lactating women, and women during menstruation; (8). Those allergic to the study drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of wound healing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound pain rating;Wound exudate scoring;Wound healing time;wound healing-related growth factors:;inflammatory factors;oxidative stress indicators; | — |
Countries
China
Contacts
Public ContactLiao Pan
The Second Affiliated Hospital of Hunan University of Chinese Medicine
Outcome results
None listed