Chronic Obstructive Pulmonary Disease (COPD)
Conditions
Interventions
Observation group:Conventional Western medical treatment plus Huagai San-based herbal decoction
Sponsors
Hebei Provincial Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet both the TCM and Western medical diagnostic criteria for AECOPD and have moderate to severe disease with 30% < FEV1% pred < 80%; 2. Patients aged between 40 and 80 years old; 3. Non-critically ill patients who are conscious and have oxygen saturation = 90%; 4. Patients with a duration of acute exacerbation < 7 days; 5. Patients who have not used probiotics or prebiotics in the past month; 6. Patients who have voluntarily signed the informed consent form and are willing to cooperate to complete the entire research process.
Exclusion criteria
Exclusion criteria: 1. Critically ill patients with SpO2 = 90% or FEV1% predicted = 30%; 2. Patients with concurrent bronchial asthma, pneumonia, tuberculosis, lung cancer, or other pulmonary diseases; 3. Patients with severe dysfunction or failure of major organs such as heart, liver, or kidneys; 4. Patients with gastrointestinal diseases such as peptic ulcer bleeding or intestinal obstruction, or those allergic to the study medication; 5. Patients who have used corticosteroids, immunosuppressants, or antibiotics within the past 2 weeks; 6. Pregnant or breastfeeding women, or patients with mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Efficacy Evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Related Exposure Factors;TCM syndrome score;CAT Score;CRP level;Gut microbiota distribution;Adverse Reaction; | — |
Countries
China
Contacts
Public ContactGuo Jie
Hebei Provincial Traditional Chinese Medicine Hospital
Outcome results
None listed