Ischemic Stroke
Conditions
Interventions
Conventional Acupuncture Group:Conventional acupuncture treatment combined with basic therapy and rehabilitation training. For upper limb motor dysfunction: Jianyu (LI15), Quchi (LI11), Waiguan (TE5),
DU Meridian Acupuncture Group:Based on conventional acupuncture group treatment, add DU Meridian acupuncture at Shenting (GV24), Baihui (GV20), Fengfu (GV16), and Dazhui (GV14). Retain needles for 30
Sponsors
Guangzhou University of Traditional Chinese Medicine First Affiliated Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients must meet the diagnostic criteria of both Western medicine and Traditional Chinese Medicine, with a disease course of more than 2 weeks but less than 6 months, and be in the recovery phase; (2) All patients must have no history of ischemic or hemorrhagic stroke prior to this incident, and this must be their first occurrence; (3) Patients must be aged between 40 and 75 years old; (4) The infarct lesion must be located in the unilateral motor pathway (unilateral basal ganglia and/or corona radiata); (5) Blood pressure must be stable below 160/100 mmHg; (6) Motor dysfunction must be related to ischemic stroke, and there must be no prior motor dysfunction caused by other diseases before the stroke; (7) Unilateral limb motor dysfunction must be present (simplified FMA score <99 points); (8) Vital signs must be stable, with no language or hearing impairments, and patients must be able to cooperate with treatment; (9) Patients must be willing to accept the treatment plan of this study, voluntarily participate in the research, and sign the informed consent form; (10) All patients must be determined to be right-handed according to the Edinburgh Handedness Inventory; (11) Patients must have a relatively stable condition and be able to cooperate with MRI scans and clinical data collection; (12) Patients must not have taken psychotropic drugs in the past month; (13) Patients must have no contraindications for MRI examinations. All patients must meet the above 13 criteria.
Exclusion criteria
Exclusion criteria: (1) Those with a history of hemorrhagic stroke and ischemic stroke; (2) Those with severe primary diseases such as heart, lung, liver, gallbladder, kidney, pancreas, hematopoietic system diseases, and malignant tumors; (3) Those with poor compliance or severe aphasia, severe hearing impairment, intellectual disability, or comprehension that make it impossible to cooperate with the treatment plan; (4) Those with intracranial aneurysms, vascular malformations, or brain tumors; (5) Patients with severe brain dysfunction; (6) Those with hemoglobin below 100 g/L, platelet count less than 100 × 109/L, or international normalized ratio (INR) greater than 1.5 (irreversible), with uncorrectable bleeding factors; (7) Those with severe spinal deformities that affect acupuncture at the Governor Vessel; (8) Those with contraindications for MRI examinations, such as implanted metal devices or claustrophobia; (9) Those with severe intracranial anatomical asymmetry or clear lesions found in MRI scan results. If any of the above applies, exclusion is warranted.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Limb Function Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| National Institutes of Health Stroke Scale;Modified Barthel Index;Serum Vasoactive intestinal polypeptide;Serum Substance P;Functional Magnetic Resonance Imaging; | — |
Countries
China
Contacts
Public ContactHe Jun
Guangzhou University of Traditional Chinese Medicine First Affiliated Hospital
Outcome results
None listed