Liver Injury
Conditions
Interventions
Experimental Group:Compound Jigucao (Abrus cantoniensis) Capsule
Control Group:HuGanPian
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Age = 18 years old and = 60 years old (including cut-off value); (2) Gender is not limited; (3) Patients with mixed and grade 1 liver impairment who meet the diagnostic criteria: (1) have liver-related clinical symptoms such as right upper quadrant pain nausea vomiting etc.; (2) Abnormal liver function found by laboratory examination ALT AST=2 upper limit of normal (ULN) or ALP=2×ULN and TBil<2×ULN2<R<5; (4) The TCM syndrome is consistent with the hepatobiliary dampness and heat pattern; (5) Voluntarily participate in this trial and be able to comply with the treatment plan and follow-up requirements specified in the study; (6) The subject himself gave informed consent and voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Advanced liver diseases such as cirrhosis and liver cancer; (2) Concurrent severe diseases affecting vital organs like the heart brain or kidneys; (3) Liver damage caused by surgical conditions; (4) Patients with unclear consciousness or communication barriers who cannot cooperate with the study (e.g. severe cognitive impairment mental illness etc.); (5) Patients allergic to the ingredients of Compound Coptis Rhizoma Capsules or with a history of other drug allergies; (6) Women who are breastfeeding or pregnant; (7) Patients who have recently (within 3 months before the start of the study) received treatment for liver diseases such as liver-protective drugs; (8) Patients who cannot follow up on schedule or cannot complete the entire treatment period; (9) Patients participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine Aminotransferase;Aspartate Aminotransotransferase; | — |
Secondary
| Measure | Time frame |
|---|---|
| Coagulation Function;TCM Syndrome Score; | — |
Countries
China
Contacts
Public ContactXiaoke Li
Dongzhimen Hospital Beijing University of Chinese Medicine
Outcome results
None listed