Diminished ovarian reserve
Conditions
Interventions
Combined Therapy Group:Photodynamic therapy + Traditional Chinese Medicine (Dingkun Dan)
TCM Group:Dingkun Dan Therapy
Western Group:Photodynamic Therapy + Placebo (Dingkun Dan Simulant)
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Females (aged 25-40 years);2) Patients who meet the diagnostic criteria for TCM (Traditional Chinese Medicine) syndromes of kidney deficiency and imbalance between yin and yang of the kidney;3) Patients who meet the DOR diagnostic criteria
Exclusion criteria
Exclusion criteria: 1) Patients with organic lesions such as ovarian tumors, pituitary adenomas, endometrial tuberculosis, intrauterine adhesions or endometrial damage after induced abortion, as well as those with polycystic ovary syndrome, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, or thyroid dysfunction;2) Women with infertility who have received sex hormone therapy in the past 3 months;3) Patients with severe or unstable physical diseases, involving the liver, kidney, gastrointestinal, cardiovascular, respiratory, endocrine, neurological, immune, hematological, or neuropsychiatric systems;4) Patients with substance (alcohol or drug) abuse or dependence in the past 3 months; heavy smokers (those who smoke 20 or more cigarettes per day);5) Patients with a history of allergy to the study drug or photosensitivity, or with contraindications to Dingkun Dan;6) Patients who have participated in a clinical trial of another study drug within 1 month before being included in this study (first interview);7) Other conditions that may reduce the possibility of enrollment or complicate enrollment, as judged by the researcher, such as frequent changes in work environment which may easily lead to loss of follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovarian reserve function assessment indicators (AMH, AFC, FSH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical indicators;Menstrual flow scale;Traditional Chinese Medicine symptom scale;Quality of life scale; | — |
Countries
China
Contacts
Public ContactSun Aijun
Peking Union Medical College Hospital
Outcome results
None listed