Skip to content

Clinical efficacy evaluation and brain functional network imaging characteristics of Yijinjing intervention in knee osteoarthritis

Clinical efficacy evaluation and brain functional network imaging characteristics of Yijinjing intervention in knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002438
Enrollment
Unknown
Registered
2025-12-10
Start date
2025-12-15
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Yijinjing Exercise Group:Yijinjing
Stretching Exercises group:Stretching Exercises

Sponsors

Shanghai Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Meets the KOA diagnostic criteria established by the American College of Rheumatology; 2) Age 40-80 years old, male or female, right-handed; 3) At least one knee has mild to moderate tibiofemoral or patellofemoral arthritis (unilateral or bilateral knee joint X-ray Kellgren Lawrence grading 1-3); 4) At least one of the 5 questions related to WOMAC pain has a score of = 40; 5) Clear consciousness, answering questions accurately, able to understand the clauses of various scales and complete the assessment; 6) Agree to participate in the survey and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1) History of knee joint surgery or concurrent knee joint tumors, tuberculosis, osteomyelitis; 2) Arthroscopic examination in the past 6 months or intra-articular injection of hormones or hyaluronic acid in the past 3 months; 3) The physical and mental conditions assessed and diagnosed by doctors, including severe acute and chronic organic diseases of the heart, liver, kidney, cerebrovascular, and hematopoietic systems, recent stroke, mental illness, and active cancer, cannot be safely exercised; 4) Participate in strength training for more than 30 minutes per week in the past 3 months; 5) I have participated in other clinical trials within the past 12 weeks.

Design outcomes

Primary

MeasureTime frame
WOMAC;

Secondary

MeasureTime frame
Pressure Pain Threshold Assessment;Muscle Stiffness Assessment;Muscle Strength Assessment;Electromyography (EMG) Assessment;the 21-item version of the Depression Anxiety Stress Scales;the 36-Item Short Form Health Survey;Brain MRI;Lower Limb Muscle MRI ;

Countries

China

Contacts

Public ContactFei Yao

Shanghai University of Traditional Chinese Medicine

doctoryaofei@126.com13585975106

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026