parkinson disease
Conditions
Interventions
Waiting group: Anti-Parkinson drugsd
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meets diagnostic criteria for PD and insomnia, with insomnia onset occurring after PD diagnosis; (2) Male or female, aged 35–80 years; (3) Patient voluntarily participates in this study and signs written informed consent; (4) Pittsburgh Sleep Quality Index (PSQI) score >7; (5) Hoehn and Yahr staging of 1–3; (6) No use of adjunctive medications beyond stable baseline PD therapy; if used, a washout period (typically 3–7 days) must be completed before study inclusion.
Exclusion criteria
Exclusion criteria: (1) Patients with secondary Parkinson's disease, Parkinsonian syndromes, or other conditions suspected to be related to the patient's symptoms, such as Parkinson's superimposed syndromes or senile tremor; (2) Confirmed severe systemic diseases, such as stroke, malignant tumors, renal failure, diabetes, atrial fibrillation, etc.; (3) Patients with confirmed cortical sensory loss, ideomotor apraxia, or progressive aphasia; (4) Patients with severe cognitive impairment, blindness, deafness, or other conditions preventing adequate cooperation; (5) Patients with depression, severe anxiety disorders, psychotic states, schizophrenia, or other major psychiatric disorders; (6) Presence of other conditions or factors affecting sleep quality, such as drug, alcohol, or caffeine addiction; (7) Fear of acupuncture; (8) Refusal of anti-Parkinson's medication; (9) Acupuncture treatment contraindications: Individuals with concurrent severe life-threatening underlying conditions, or those with ulcers, abscesses, skin infections, or limb deficiencies at selected acupuncture points that preclude treatment. (10) Pregnant women or those planning pregnancy within 3 months; (11) Individuals who participated in other clinical trials involving drugs, acupuncture, or similar treatments within 1 month prior to study enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Parkinson's Disease Sleep Scale 2 ;Hamilton Anxiety Scale;Parkinson's Disease Questionnaire-39;Unified Parkinson's Disease Rating Scale;Sleep Diary;Adrenocorticotropic hormone;Cortisol;Corticotropin-releasing hormone; | — |
Countries
china
Contacts
Public ContactLixing Zhuang
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed