Premature ovarian insufficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Those who meet the Western medicine diagnosis and Chinese medicine diagnosis of early-onset ovarian insufficiency and are preparing for pregnancy; 2) 25U/L < FSH < 40U/L; 3) 25 years old < age < 40 years old; 4) Volunteer to participate in the research and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with other tubal and endocrine diseases such as salpingitis, hyperprolactinemia, thyroid dysfunction; 2) Patients with congenital genital malformations and chromosomal abnormalities; 3) Patients with severe heart, liver, kidney, malignant tumors and mental system diseases; 4) He has a history of taking hormone drugs in the past 3 months, a history of severe acupuncture dizziness and dizzy moxibustion, and allergies or severe allergies to the drugs in this study; 5) Patients receiving other treatment options (such as surgery, etc.) during treatment; 6) POI caused by iatrogenic factors (such as pelvic surgery, chemoradiotherapy, uterine artery embolization, drugs such as hormones, immunosuppressants, etc.); 7) Patients with severe cardiovascular, cerebrovascular, liver, kidney, malignant tumors, hematopoietic system and mental diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antral Follicle Count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sex hormone(Follicle-stimulating hormone Luteinizing hormone Estradiol);Anti-Mullerian hormone;Local blood flow indicators of the ovary(Pulsatility index Resistent index Peak systolic velocity);Menstrual condition;Kupperman Scale score;Self-rating Anxiety Scale score;Traditional Chinese Medicine Syndrome score;Pregnancy rate; | — |
Countries
China
Contacts
The First Affiliated Hospital of Guizhou University of Chinese Medicine