Polycystic Ovary Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Individuals with polycystic ovary syndrome: 1) Aged 20–40 years with a desire to conceive; 2) Meeting the Rotterdam criteria established in May 2003 by the European Society of Human Reproduction and Embryology and the American Society for Reproductive Medicine (ESHRE/ASRM); 3) Voluntarily participating in this clinical study and signing an informed consent form. Healthy participants: 1) Aged 20–40 years with a desire to conceive; 2) Regular menstrual cycles within the past year; 3) No significant abnormalities detected by ultrasound; 4) Voluntary participation in this clinical study with signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Conditions exhibiting clinical and endocrine manifestations similar to PCOS, such as thyroid dysfunction, premature ovarian failure, hyperprolactinemia, congenital adrenal hyperplasia, androgen-secreting tumours, or Cushing's syndrome; 2) Patients with concomitant malignancies, severe cardiovascular, hepatic, renal, or haematopoietic disorders, or psychiatric conditions; 3) Presence of other infertility factors, such as genital malformations; 4) Recent use of hormonal medications within the past three months; 5) Individuals with sexually transmitted infections or inflammatory conditions of the genitourinary system; 6) Pregnant individuals; 7) Concurrent participation in other clinical studies that may compromise the integrity of this investigation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation is related;Lymphocyte subsets;Reproductive endocrine indicators;Endometrial receptivity;Menstruation;Intestinal microflora; | — |
Countries
CHINA
Contacts
Dongzhimen Hospital of BeijingUniversity of Chinese Medicine