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A clinical study on the effect of acupoint application of traditional Chinese medicine in alleviating abdominal pain during hyperthermic intraperitoneal perfusion therapy

Acupoint application of traditional chinese medicine Mitigates hyperthermic intraperitoneal perfusion therapy-associated abdominal pain: A Non-Invasive Analgesic Strategy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025002371
Enrollment
Unknown
Registered
2025-12-06
Start date
2023-05-08
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eligible patients undergoing hyperthermic intraperitoneal perfusion therapy were enrolled as research subjects

Interventions

Group A (experimental) :Standard analgesic therapy combined with traditional chinese medicine acupoint application at Shenque, Zhongwan, Zusanli, and Ashi points.
Group B (control):A placebo patch with conventional analgesic treatment at Shenque, Zhongwan, Zusanli, and Ashi points.

Sponsors

Jinan Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) patients aged 18-80 years, with malignant tumors confirmed pathologically, or postoperative patients with definitive pathological diagnosis, in accordance with National Comprehensive Cancer Network (NCCN) or Chinese Society of Clinical Oncology (CSCO) guidelines recommending HIP therapy, with complete clinical data available; (2) adequate bone marrow, hepatic, cardiac, renal, and coagulation function; (3) absence of clinically significant comorbidities; (4) expected survival of more than 3 months; (5) voluntary participation with signed informed consent.

Exclusion criteria

Exclusion criteria: (1) absence of definitive pathological diagnosis; (2) severe pelvic-abdominal adhesions, intestinal obstruction, gastrointestinal diseases, or acute or chronic intra-abdominal infections prior to HIP; (3) severe cardiac, hepatic, pulmonary, renal, or cerebral dysfunction; (4) bleeding tendency; (5) contraindications to HIP or surgery; (6) thermoregulatory or sensory disorders; (7) inability to communicate normally; (8) irregular treatment or incomplete data.

Design outcomes

Primary

MeasureTime frame
Pain evaluation:Visual analogue scales;Quality of life assessment: Karnofsky Performance Status scale;

Countries

China

Contacts

Public ContactChunhui Lu

Jinan Third People's Hospital

lch1991@126.com15764170977

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026