Postoperative pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients scheduled for elective video-assisted thoracoscopic surgery (VATS) for pulmonary wedge resection 2) Aged 18 to 65 years; 3) American Society of Anesthesiologists (ASA) physical status classification = Class II; 4) Body mass index (BMI) <25 kg/m²; 5) Voluntarily participate and provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients who refused the proposed surgical and anesthetic protocols; 2) Contraindications to general or regional anesthesia including: Respiratory disorders: laryngeal edema acute laryngitis laryngeal submucosal hematoma severe asthma chronic obstructive pulmonary disease (COPD) recent severe upper respiratory infection or pneumonia Cardiovascular diseases: unstable angina poorly controlled hypertension (resting BP >160/100 mmHg) acute myocardial infarction within 6 months Coagulopathy Inadequate fasting duration (40 cm) Physical examination findings: • Mallampati class =II • Thyromental distance =6 cm • Mentohyoid distance =12 cm • Inadequate jaw protrusion (<1 cm advancement) • Restricted neck flexion-extension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remifentanil consumption during operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total intraoperative and 48-hour postoperative sufentanil consumption;Visual Analog Scale (VAS) scores assessed at: ??2 hours postoperatively (T1)?? ??6 hours postoperatively (T2)?? ??24 hours postoperatively (T3)?? ??48 hours postoperatively (T4)?;otal intraoperative consumption of propofol and vasoactive agents;Opioid dosage within 48 hours after surgery, calculated as morphine equivalents;Postoperative recovery time, extubation time and hospitalization time;Number of PCIA device compressions, effective compressions, and rescue analgesia within 48 hours after surgery;Adverse events such as postoperative vomiting (PONV), drowsiness, respiratory depression (SpO2 < 90%), and skin itching within 48 hours;The quality of recovery was scored using the postoperative QoR-15 scoring scale.;The Postoperative Quality Recovery Scale (PQRS) was used to evaluate the quality of postoperative recovery and patient satisfaction after anesthesia.; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine