Varicocele with Oligoasthenospermia
Conditions
Interventions
Buyu No.1 Formula + Placebo (Tablet) Group:The treatment involves taking the kidney-tonifying Buyu No.1 Formula ready-to-drink granules and Mai Zhiling placebo tablets (as a control), with a 12-week c
B (Mai Zhiling tablets + placebo (granules) group):Treatment involves taking Mesilium tablets and Chinese herbal placebo (granules), with a 12-week course. Mesilium tablets: 2 tablets per dose, twice
Sponsors
Beijing University of Chinese Medicine Dongzhimen Hospital
Eligibility
Sex/Gender
Male
Age
22 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Males aged between 22 and 50 years (inclusive of 22 and 50 years); (2) Meet the diagnostic criteria for varicocele with oligoasthenospermia; (3) Have not taken medications for the treatment of varicocele or oligoasthenospermia within the past month; (4) Are able to maintain a regular sexual life; (5) Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Non-varicocele-associated oligoasthenozoospermia; (2) Combined with congenital malformations, underdeveloped or atrophic testes, chromosomal abnormalities, genitourinary system infections, endocrine disorders, etc.; (3) Spouse infertility; (4) Combined with abnormal liver or kidney function, neurological diseases, cardiovascular diseases, or other severe primary diseases of other systems; (5) Allergy to the drugs used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total sperm motility (PR + NP);Sperm concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sperm DNA Fragmentation Index (DFI);Internal diameter of the spermatic vein;TCM syndrome score;Spouse Pregnancy Status; | — |
Countries
China
Contacts
Public ContactWang Bin
Beijing University of Chinese Medicine Dongzhimen Hospital
Outcome results
None listed