Osteoarthritis of the knee (blood stasis syndrome)
Conditions
Interventions
Short Thrust Needling Group:Acupoint Selection: On the affected side: Duba (ST36), Neixiye (ST35), Zhongwan (CV3), Liangqiu (ST34), Zusanli (ST36), Yanglingquan (GB34), Yinlingquan (SP9), and Xuehai (
Zusanli and Yanglingquan are obliquely inserted toward Zhongwan at a 45° angle to the skin, 35–50 mm deep, until the needle tip reaches the fibula
Yinlingquan is obliquely inserted toward Zhongwan at a 45° angle to the skin until the needle tip reaches the tibia. All points are needled slowly, gradually advancing while oscillating the needle bod
Sham acupuncture group:Acupoint Selection: On the affected side: Duba (ST36), Neixiye (ST35), Pouchong (ST37) (located below the patellar apex, midway between Duba and Neixiye), Liangqiu (ST34), Zusan
Sponsors
Shanghai University of Traditional Chinese Medicine Affiliated Putuo Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Meets both Western medical diagnostic criteria for KOA and criteria for blood stasis obstruction syndrome (Western medical criteria: refer to the 1995 American College of Rheumatology revised international diagnostic criteria for knee osteoarthritis, including 1) knee pain present most of the time during the past month; 2) radiographic evidence of osteophyte formation; 3) Synovial fluid analysis consistent with osteoarthritis (clear, viscous, white blood cell count <2×10^9/L); 4) Age =40 years; 5) Morning stiffness <30 minutes; 6) Crepitus during joint movement. Diagnosis of knee osteoarthritis requires presence of 1) and 2), or 1) and 3), 5), 6), or 1), 4), 5), 6). TCM Diagnostic Criteria: Refer to the 2012 edition of the Chinese Industry Standard for Traditional Chinese Medicine Diagnosis and Treatment Efficacy Criteria ZY/T001.1-94 (China Traditional Chinese Medicine Press): 1) Stabbing pain in the knee joint with localized tenderness; 2) Restricted knee joint mobility; 3) Dark purple tongue with deep or fine-thready pulse. (3) Age 40–75 years; (4) Radiographic grading of knee osteoarthritis as Kellgren-Lawrence Grade I–III; (5) Disease duration =10 years with recent onset of knee functional impairment; (6) Patients conscious and able to understand and complete questionnaires; (7) Voluntary participation in this trial with signed informed consent; (8) Full legal capacity.
Exclusion criteria
Exclusion criteria: (1)Lesions with skin ulceration, infection, or other conditions unsuitable for acupuncture treatment; (2)Knee issues caused by other diseases; (3)Severe cardiovascular diseases, severe infections, mental disorders, or tumors; (4)Use of other treatment methods within the past month, which may affect the evaluation of treatment efficacy; (5)Individuals who have undergone knee joint surgery; (6)Pregnant, postpartum, or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the Western Ontario and McMaster Osteoarthritis Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Infrapatellar Fat Pad Morphometric Measurement Under Musculoskeletal Ultrasound;Echogenicity Changes of Infrapatellar Fat Pad on Musculoskeletal Ultrasound;Musculoskeletal Ultrasound-Guided Blood Flow Perfusion of Infrapatellar Fat Pad;Visual Analogue Scale score;Knee joint range of motion; | — |
Countries
China
Contacts
Public ContactGu Yuehua
Shanghai University of Traditional Chinese Medicine Affiliated Putuo Hospital
Outcome results
None listed