unstable angina
Conditions
Interventions
experimental group:Qingtan Huayu Formula Granules: Take 2 bags twice daily (morning and evening), dissolved in warm water, for a 4-week treatment course
control group:Placebo Granules: Take 2 bags twice daily (morning and evening), dissolved in warm water, for a 4-week period
Sponsors
The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1)Aged 18-79 years, regardless of sex;2) History of percutaneous coronary intervention (PCI) for coronary heart disease;3) Meeting diagnostic criteria for unstable angina per Western medicine standards;4) Diagnosed with phlegm-heat blood stasis syndrome (TCM pattern);5) Voluntarily accepting Chinese herbal ;ecoction therapy;6) No use of Chinese herbal pieces or proprietary Chinese medicines within the preceding 2 weeks;7) Provided written informed consent after full explanation of study objectives and procedu
Exclusion criteria
Exclusion criteria: 1) Life-threatening comorbidities: pulmonary embolism, acute heart failure, respiratory failure, acute cerebral hemorrhage, acute myocardial infarction, severe arrhythmia, cardiac systolic dysfunction (LVEF 2×ULN and/or creatinine >2×ULN);9) Declined to sign informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Angina Symptom Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seattle Angina Questionnaire;Score of traditional Chinese medicine syndrome scale;Overall Response Rate;Left Ventricular Ejection Fraction;Left Ventricular End-Diastolic Dimension;Triglycerides;Total Cholesterol;Low-Density Lipoprotein Cholesterol;C-reactive Protein;High-Sensitivity C-reactive Protein;Interleukin-6;High-Density Lipoprotein Cholesterol;Trimetlylamine oxide; | — |
Countries
China
Contacts
Public ContactBi Yingfei
The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed