Parkinson's disease
Conditions
Interventions
Experimental Group:Electroacupuncture
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with Parkinson's disease according to the 2015 International Parkinson and Movement Disorder Society (MDS) clinical diagnostic criteria for Parkinson's disease; (2) Aged 40-75 years, right-handed; (3) With a Hoehn-Yahr stage of 1-4; (4) In a relatively stable condition, with no change in medication dosage or no medication taken within the last 30 days; (5) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Severe cardiovascular and cerebrovascular diseases, liver or kidney diseases, malignant tumors, hematopoietic system diseases, or other life-threatening conditions; (2) History of alcohol or substance abuse, severe allergic constitution, severe mental disorders, or individuals with a cardiac pacemaker; (3) Pregnant or lactating women; (4) Individuals who have undergone Parkinson's disease-related surgical treatments (e.g., pallidotomy, deep brain stimulation, cervical deep venous lymph node anastomosis, etc.); (5) Participation in other clinical trials involving drugs, acupuncture, etc., within one month prior to inclusion in this study; (6) Inability to tolerate MRI or color Doppler ultrasound examinations; (7) Unsuitable for acupuncture due to reasons such as skin lesions at the operation site; (8) Inability to comply with the treatment protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MDS-UPDRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| PET-MRI;fMRI;DTI-ALPS;MSUS;TCS;Contrast-Enhanced Transcranial Ultrasound;Timed Up and Go Test;Patient Health Status Questionnaire-9;Parkinson's Disease Questionnaire - 8;Parkinson's Disease Sleep Scale;HAMD-17; | — |
Countries
China
Contacts
Public ContactNing Baile
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed