Chronic kidney disease
Conditions
Interventions
the observed population:with no intervention measures
Sponsors
The Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Provincial Hospital of Traditional Chinese Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Patients who meet the diagnostic criteria for Stage 3 Chronic Kidney Disease (CKD) and the TCM pattern differentiation criteria for chronic renal failure, specifically the pattern of kidney deficiency with dampness (heat) and blood stasis. 2) Aged between 18 and 65 years, irrespective of gender. 3) Provide informed consent and volunteer to participate in the trial. The process of obtaining informed consent must adhere to the principles of Good Clinical Practice (GCP).
Exclusion criteria
Exclusion criteria: (1) Patients with severe comorbidities of major organs, such as severe hepatic dysfunction (transaminase levels >3 times the upper limit of normal), malignant tumors, severe anemia (Hb <60 g/L), or a history of cardiovascular/cerebrovascular stent implantation within the past 3 months. (2) Patients with CKD secondary to autoimmune diseases, or those currently taking corticosteroids or immunosuppressants. (3) Patients with a known allergy to any component of the Chinese herbal medicine, or those with a history of severe allergic predisposition. (4) Pregnant or lactating women. (5) Patients judged by the investigator to have poor compliance or who are otherwise deemed unsuitable for trial participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| estimated Glomerular Filtration Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| renal function;urinary albumin/creatinine ratio;complete blood count;blood lipids;iron metabolism; | — |
Countries
China
Contacts
Public ContactWeiming HE
The Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Provincial Hospital of Traditional Chinese Medicine)
Outcome results
None listed