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Mechanism Study on the Intervention of Treg/Th17 Pathway with Moxibustion Isolation in the Treatment of elderly Hashimoto's Thyroiditis

Mechanism Study on the Intervention of Treg/Th17 Pathway with Moxibustion Isolation in the Treatment of elderly Hashimoto's Thyroiditis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002276
Enrollment
Unknown
Registered
2025-11-21
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hashimoto's thyroiditis

Interventions

Experimental group Control group:herbal-partitioned moxibustion plus Take Levothyroxine orally
Control group:Basic treatment only

Sponsors

Huadong Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Meet the disease diagnostic criteria for Hashimoto's thyroiditis and hypothyroidism; (2) Age: 60-80 years old gender not limited; (3) Those who have signed the informed consent form. If all the above three conditions are met simultaneously the candidate will be included in the study.

Exclusion criteria

Exclusion criteria: (1) Patients with thyroid malignant tumors or those who have undergone surgery for thyroid malignant tumors; (2) Combined with other endocrine diseases or thyroid abnormalities; (3) Taking drugs that may affect the level of thyroid-related antibodies in the past month; (4) Those with other autoimmune diseases, such as Sjogren's syndrome, systemic lupus erythematosus, etc. (5) Suffering from severe diseases of the cardiovascular and cerebrovascular, blood, kidney, liver and other systems or being severely infected; (6) Those with abnormal mental manifestations or a history of mental illness; (7) Pregnant or lactating women; (8) There are contraindications for the experimental therapy, including skin infection or severe skin lesions at the moxibustion site, and the subject is allergic to the traditional Chinese medicine components in the medicinal cake. If any one of the above conditions is met, it will be excluded.

Design outcomes

Primary

MeasureTime frame
Thyroid-Stimulating Hormone;Thyroglobulin antibody;

Secondary

MeasureTime frame
Free Triiodothyronine;Free Thyroxine;Thyroid-Stimulating Hormone;Interleukin-17;Interleukin-10;Regulatory T cells;T helper cell 17;

Countries

China

Contacts

Public ContactLiumiaomiao

Huadong Hospital Affiliated to Fudan University

9465665932@qq.com15618770317

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026